EOSC4Cancer Longitudinal Synthetic Colorectal Cancer Genomic data developed at BSC

The synthetic genomes have been created trying to mimic real cancer data of 4 patients (Named 185, 186, 187, and 188). Mutations are based on real CRC patients from the PCAWG dataset. For each patient, two tumor samples at different time points and one healthy sample have been simulated. The cancer intra-tumor heterogeneity and evolution in the patients is depicted by simulating reads from tumor subclones separately and then mixing them according to their clonal proportions in each sample. For rapid use and transfer, only selected chromosomes have been generated for each patient. For Beacon queries, the following url can be used https://gdi-beacon-prototype.azurewebsites.net/api/datasets/EGAD50000000276

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Additional Info

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Title EOSC4Cancer Longitudinal Synthetic Colorectal Cancer Genomic data developed at BSC
Description

The synthetic genomes have been created trying to mimic real cancer data of 4 patients (Named 185, 186, 187, and 188). Mutations are based on real CRC patients from the PCAWG dataset. For each patient, two tumor samples at different time points and one healthy sample have been simulated. The cancer intra-tumor heterogeneity and evolution in the patients is depicted by simulating reads from tumor subclones separately and then mixing them according to their clonal proportions in each sample. For rapid use and transfer, only selected chromosomes have been generated for each patient. For Beacon queries, the following url can be used https://gdi-beacon-prototype.azurewebsites.net/api/datasets/EGAD50000000276
Keywords
Contact points
Contact point 1
URI
Name
Servicedesk Health-RI
Name (translations)
Email
servicedesk@health-ri.nl
Identifier
https://ror.org/05wg1m734
Publisher
Publisher 1
URI
Name
Health-RI
Name (translations)
Email
servicedesk@health-ri.nl
URL
https://www.health-ri.nl/
Type
Identifier
https://ror.org/05wg1m734
Creator
Creator 1
URI
Name
BSC
Name (translations)
Email
info@bsc.es
URL
https://www.bsc.es/
Type
Identifier
https://ror.org/05wg1m734
Landing page
Release date 2025-01-29T11:11:11+00:00
Modification date 2025-01-29T13:36:10+00:00
Temporal start date
Temporal end date
In Series
    Version
    Version notes
    Identifier EGAD50000000276
    Frequency
    Provenance
    Type
    Temporal coverage
    Temporal resolution
    Spatial coverage
    Spatial resolution in meters
    Access rights http://publications.europa.eu/resource/authority/access-right/PUBLIC
    Other identifier
    Theme
    1. http://publications.europa.eu/resource/authority/data-theme/HEAL
    Language
    1. http://id.loc.gov/vocabulary/iso639-1/en
    Documentation
    Conforms to
    1. https://gdi-fdp-test.healthdata.nl/profile/2f08228e-1789-40f8-84cd-28e3288c3604
    Is referenced by
    Analytics
    Applicable legislation
    Has version
    Code values
    Coding system
    Purpose
    Health category
    Health theme
    Legal basis
    Minimum typical age 1
    Maximum typical age 100
    Number of records 10
    Number of records for unique individuals. 4
    Personal data
    Publisher note
    Publisher type
    Trusted Data Holder
    Population coverage

    This test dataset covers no real population.
    Retention period
    Health data access body
    Qualified relation
    Provenance activity
    Qualified attribution
    Quality annotations
    URI https://gdi-fdp-test.healthdata.nl/dataset/38ab26f0-dd2f-4dd8-b128-1343b6d57bbb